Curcumin nkibintu bisanzwe birinda umutobe wa Apple NFC: KubuzaAlicyclobacillus acideoterrestris

Amavu n'amavuko: Impamvu Alicyclobacillus ikomeje kuba ingorabahizi mumitobe ya NFC

Ntabwo - kuva - imitobe yimbuto (NFC) imitobe yimbuto igenda itoneshwa uburyohe bushya kandi isukuye - ikirango. Nyamara, uburyo bwabo bwo gutunganya butuma nabo bashobora kwibasirwa cyane na mikorobe yangirika - cyane cyane kuvaAlicyclobacillus acideoterrestris, acideophilique nubushyuhe - spore irwanya - ikora bagiteri.

Iyi mikorobe irashobora kurokoka uburyo busanzwe bwa pasteurizasiya, gukura mubihe bya acide (pH 2.0-6.0), kandi bigatanga umusaruro - nka guaiacol, biganisha ku kwangirika kwibicuruzwa nta bimenyetso byerekana hakiri kare. Nkigisubizo,A. acideoterrestrisifatwa cyane nkimwe mubinyabuzima byangiza cyane mugutunganya umutobe wa pome.

Hamwe nogukomeza kugenzura no kugabanya umuvuduko wabaguzi kugirango bagabanye imiti igabanya ubukana, ibisubizo byica mikorobe birakenewe byihutirwa.

Kuki Curcumin?

Curcumin ni ifumbire ya polifenolike ikomoka kuri turmeric (Kurcuma). Yemerewe gukoresha ibiryo mu bihugu byinshi kandi izwi cyane kubera antioxydants, anti - inflammatory, na mikorobe.

Ibyiza byingenzi bya curcumin muri sisitemu y'ibinyobwa bya aside birimo:

Guhagarara mubihe bya acide pH

Inkomoko y'ibimera karemano, ikwiranye ningamba zisukuye -

Imikorere ibiri nka antioxydeant na anticicrobial agent

Nuburyo bukoreshwa muri sisitemu yibiribwa, ibimenyetso bishyigikira imikorere ya curcumin kurwanyaA. acideoterrestrismuri NFC umutobe wimbuto wagabanutse - kugeza vuba aha.

Ibisubizo by'ingenzi: Igikorwa cya Antibacterial KurwanyaA. acideoterrestris

Ubushakashatsi buherutse gukorwa bwasuzumye gahunda yo guhagarika ibikorwa bya curcumin kurwanyaA. acideoterrestrisno kuyikoresha muri NFC umutobe wa pome.

Kwibanda Ntarengwa (MIC)

MIC ya curcumin kurwanyaA. acideoterrestrisyari yiyemeje kuba0.1 mg / mL

Mubitekerezo Birenze cyangwa bingana na 0.1 mg / mL, imikurire ya bagiteri yarahagaritswe neza

Ingaruka ya antibacterial yerekanaga dose iterwa

Ibisubizo byerekana ko curcumin ishobora guhagarika iyi bagiteri yangirika cyane.

Uburyo bwibikorwa: Uburyo Curcumin ibuza Bagiteri

Uburyo bwinshi bwo gusesengura bwerekanye ko curcumin igira ingaruka za antibacterial cyane cyane muguhagarika ingirabuzimafatizo.

1. Ibyangiritse kuri selile Membrane Ubunyangamugayo

Curcumin yongerera membrane permeability, itera kumeneka kwa ion na electrolytite. Ibi byashimangiwe nubwiyongere bukabije bwimyanya ndangagitsina hamwe na fluorescence - ishingiye ku busugire bwa membrane.

2. Kugabanya Urwego rudasanzwe rwa ATP

Mugihe ubunyangamugayo bugenda bwangirika, ibice bigize ATP bigabanuka cyane. Ibi biragaragaza imbaraga za metabolisme zangirika kandi bigabanya imbaraga za selile.

3. Ihungabana ryimyanya ndangagitsina pH Homeostasis

Kuvura curcumin biganisha ku kugabanuka kugaragara kwa pH idasanzwe. Iyi aside irinda kandi ibikorwa bya metabolike kandi byihutisha urupfu rwa bagiteri.

Hamwe na hamwe, ubwo buryo bwerekana ko curcumin ikora binyuze muri membrane - intego yibice - ibyangiritse bifitanye isano aho kuba inzira imwe ya antibacterial.

Imikorere muri NFC Sisitemu Yumutobe wa Apple

Kugirango hamenyekane - kwisi kwisi, curcumin yinjijwe mumitobe ya pome ya NFC hanyuma isuzumwa haba muri firigo ikonje (dogere 4) hamwe nubushyuhe bwicyumba (dogere 25).

Ingaruka zirwanya mikorobe

Kuri 1 × na 2 levels MIC urwego, birashobokaA. acideoterrestriskubara byagabanutse ubudahwema mugihe cyo kubika

Ingaruka yo kubuza yagaragaye cyane mububiko bwa firigo, byerekana ubufatanye hamwe nimbeho -

Ingaruka ku bwiza bw umutobe

Icyangombwa, kongeramo curcumin yakozentabwogutandukana cyane nibintu byingenzi bya fiziki ya chimique yumutobe:

pH:yagumye ihagaze hafi 3.29

Ibirimo isukari:~ 13.3 dogere Brix

Itandukaniro ryamabara (ΔE):Ntibiri munsi cyangwa bingana na 0,63 (ntibigaragara)

Ibirimo byose bya fenolike:yiyongereye kubera imiterere ya curcumin

Ibi birerekana ko curcumin ishobora kuzamura mikorobe mugihe ikomeza ubuziranenge bwibicuruzwa.

Ingaruka kubakora imitobe nabaguzi bingirakamaro

Ibyavuye mu bushakashatsi bishyigikira curcumin nkumukandida utanga ibyiringiro byo kubungabunga ibinyobwa bya aside, cyane cyane umutobe wa pome wa NFC.

Inyungu zishobora kuba zirimo:

Kugenzura ubushyuhe - birwanya bagiteri zangirika

Guhuza isuku - ikirango hamwe nibintu bisanzwe

Guhuza n'imbeho - sisitemu yo kubika urunigi

Wongeyeho antioxydants agaciro binyuze muri fenolike yiyongereye

Ibindi bikorwa birakenewe kugirango dusuzume inganda - igipimo cyo gutunganya igipimo, imikoranire nizindi mbogamizi zo kubungabunga, hamwe nigihe kirekire - igihe gihamye - ariko ishingiro ryubumenyi rimaze gushingwa neza.

Umwanzuro

Curcumin yerekana ibikorwa byingenzi byo kubuza kurwanyaAlicyclobacillus acideoterrestrisbinyuze mu guhungabana kwa membrane, kugabanuka kwingufu, hamwe nuburinganire bwimikorere ya pH. Iyo ushyizwe kumitobe ya pome ya NFC, irwanya neza imikurire ya bagiteri itagize ingaruka mbi kubiranga ubuziranenge.

Ibisubizo bitanga urufatiro rukomeye rwa siyanse mugutezimbere curcumin - ingamba zo kubungabunga ibidukikije muri sisitemu y'ibinyobwa bya aside.

Ibirimo bishingiye ku rungano - rwasuzumye ubushakashatsi bwakozwe kandi bugenewe inzobere mu nganda z’ibiribwa n’abateza imbere ibikoresho.