Ni ukubera iki amababi ya Mulberry akuramo impuguke ya kamere mugutunganya Glucose Metabolism?

1. Ibimera bya Botanika & Gukoresha Gakondo

Ikibabi cya Mulberry (Morus alba L.) kirimo:

1-Deoxynojirimycin (DNJ)(0.1 - 0.3%) - Imbaraga -glucosidase inhibitor

Flavonoide(quercetin, isoquercitrin)

Polifenol(aside ya chlorogene, rutin)

Amateka yamateka:

Compendium ya Materia Medica yanditse inyandiko zayo zirwanya -

Abayapani gakondo "diyabete - icyayi cyo kwirinda"

2. Ibyingenzi byingenzi nuburyo bukoreshwa

2.1 Amabwiriza ya Glucose Metabolism

2.2 Bioactives & Intego

3. Ubuziranenge

3.1 Kwemeza

Microscopi: Ibiranga non - umusatsi wa glande ufite ibibyimba byabyimbye

TLC igikumwe: Ibibanza 5 bitandukanye bisabwa

Umubare wa HPLC: Birarenze cyangwa bingana na 0.1% DNJ (Pharmacopoeia standard)

3.2 Ibisobanuro bigezweho

Pharmacopoeia yo mu Bushinwa: flavonoide Yose iruta cyangwa ingana na 1.5%

Igipimo cy'Ubuyapani: DNJ Ikomeye cyangwa ingana na 0.15%

Amabwiriza y’ubumwe bw’ibihugu by’Uburayi: Ibisigisigi byica udukoko<0.01ppm

4. Ibimenyetso bya Clinical

4.1 Gucunga diyabete

Andika II DM: 1200mg / kumunsi bigabanya HbA1c kuri 0.8-1.2%

Indwara ya Diyabete: NNT =8 kugirango wirinde indwara ya diyabete

4.2 Inyungu za Metabolic

Amabwiriza ya Lipid: 15-20% kugabanya triglyceride

Gucunga ibiro: Umuzenguruko wa 2-3cm ugabanuka (ibyumweru 12)

5. Gukoresha uburyo bwiza

5.1 Ingamba zo Kunywa

Shingiro: 300mg (30min pre - ifunguro)

Byinshi: 600mg + chromium combo

5.2 Gukomatanya

Gymnema sylvestre: Yongera imisemburo ya insuline

Alpha - aside ya lipoic: Itezimbere ikoreshwa rya glucose

Probiotics: Ihindura amara - pancreas axis

6. Ibitekerezo byumutekano

Indwara ya Hypoglycemia: Irasaba gukurikirana hamwe na antidiabete

Abarwayi bo kubaga: Hagarika icyumweru 1 pre - op

GI ibyiyumvo: Tangira ukoresheje dosiye nke

7. Igitabo cyo guhitamo ibicuruzwa

Ibicuruzwa bihebuje biranga:

Ikirango cya DNJ

Hasi - gukuramo ubushyuhe

Raporo yikizamini kiremereye

Ibibazo bisanzwe:

Gusimbuza ubwoko butandukanye - DNJ

Ubusambanyi bwa DNJ

8. Imipaka yubushakashatsi

Gut microbiota: Yongera Akkermansia ubwinshi

Gutezimbere NAFLD: Irabuza selile selile

Kuramba - gusohora: Kongera ibikorwa bya DNJ

Umwanzuro wa siyansi

Ibibabi bya Mulberry bitanga:
1️⃣ Multi - kugenzura intego(amara + umwijima + ingirabuzimafatizo)
2️⃣ Umutekano kamere(Amateka yo gukoresha imyaka 2000)
3️⃣ Inyungu zuzuye zo guhinduranya(glucose + lipide + uburemere)